hrp0094fc5.3 | Sex Development and Gender Incongruence | ESPE2021

Fetal Anogenital Distance (AGD) by Ultrasonography: a Marker of Early Androgen Exposure in utero?

Fischer Margit Bistrup , Scheel Lone , Sundberg Karin , Juul Anders , Hagen Casper P ,

Background: The anogenital distance (AGD) is defined as the distance from the anus to genital tubercle. AGD is an established method for sex determination of pups in rodents, and in animal studies, AGD is strongly affected by androgen exposure during fetal life. In accordance, human studies have reported reduced postnatal AGD following prenatal exposure to anti-androgenic agents, suggesting AGD to be a sensitive postnatal read out of in utero exposure...